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21.
Two novel amino acids imine ligands (H2L1 and H2L2) have been synthesized using green condensation reaction from 2‐[3‐Amino‐5‐(2‐hydroxy‐phenyl)‐5‐methyl‐1,5‐dihydro‐[1, 2, 4]triazol‐4‐yl]‐3‐(1H‐indol‐3‐yl)‐propionic acid with benzaldehyde/p‐flouro benzaldehyde (1:1 molar ratio) in the presence of lemon juice as a natural acidic catalyst in aqueous medium. Their transition metal complexes have been prepared in a molar ratio (1:1). Characterization of the ligands and complexes using elemental analysis, spectroscopic studies, 1HNMR, 13CNMR, and thermal analysis has been reported. E*, ΔH*, ΔS* and ΔG* thermodynamic parameters, were calculated to throw more light on the nature of changes accompanying the thermal decomposition process of these complexes. The molar conductance measurement of metal complexes showed nonelectrolyte behavior. The metal complexes of the two ligands have tetrahedral geometry with a general molecular structure [M(H2L)Xn], where [(M = Mn (II), Co (II), Cu (II) and Zn (II), X = Cl, n = 2]; M = VO (II), X = SO4, n = 1] for H2L1. [M = Co (II), Cu (II), Zn (II)] for H2L2. Antibacterial activity of the complexes against (Bacillis subtilis, Micrococcus luteus, Escherichia coli), also antifungal activity against (Aspergillus niger, Candida Glabarta, Saccharomyces cerevisiae) have been screened. The results showed that all complexes have antimicrobial activity higher than free ligands. Molecular docking studies results showed that, all the synthesized compounds having minimum binding energy and have good affinity toward the active pocket, thus, they may be considered as good inhibitor of targeting PDB code: 1SC7 (Human DNA Topo‐isomerase I). 相似文献
22.
Dr. Ritesh Haldar Kamal Batra Stefan Michael Marschner Dr. Agnieszka B. Kuc Dr. Stefan Zahn Prof. Dr. Roland A. Fischer Prof. Dr. Stefan Bräse Prof. Dr. Thomas Heine Prof. Dr. Christof Wöll 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(33):7847-7851
In organic photovoltaics, porphyrins (PPs) are among the most promising compounds owing to their large absorption cross-section, wide spectral range, and stability. Nevertheless, a precise adjustment of absorption band positions to reach a full coverage of the so-called green gap has not been achieved yet. We demonstrate that a tuning of the PP Q- and Soret bands can be carried out by using a computational approach for which substitution patterns are optimized in silico. The most promising candidate structures were then synthesized. The experimental UV/Vis data for the solvated compounds were in excellent agreement with the theoretical predictions. By attaching further functionalities, which allow the use of PP chromophores as linkers for the assembly of metal-organic frameworks (MOFs), we were able to exploit packing effects resulting in pronounced redshifts, which allowed further optimization of the photophysical properties of PP assemblies. Finally, we use a layer-by-layer method to assemble the PP linkers into surface-mounted MOFs (SURMOFs), thus obtaining high optical quality, homogeneous and crystalline multilayer films. Experimental results are in full accord with the calculations, demonstrating the huge potential of computational screening methods in tailoring MOF and SURMOF photophysical properties. 相似文献
23.
Gold nanoparticles have unique and excellent medical and nonmedical properties and application compared with other metallic nanoparticles. Recently, they have been used for the prevention, control, and treatment of bacterial and fungal diseases. In the recent study, fresh and clean leaves of Allium noeanum Reut. ex Regel leaves have been used for the synthesis of gold nanoparticles. Also, we evaluated the cytotoxicity, antioxidant, and antibacterial properties of HAuCl4, A. noeanum, and the synthesized nanoparticles (Au NPs). These nanoparticles were analyzed by FT‐IR, UV, XRD, EDS, FE‐SEM, and TEM tests. FTIR results offered antioxidant compounds in the plant were the sources of reducing power, reducing gold ions to Au NPs. In TEM images revealed an average diameter of 10‐30 nm. At the beginning of biological experiments, DPPH free radical scavenging test was carried out to examine the antioxidant property. Also, in the bacterial part of this study, the concentration of HAuCl4, A. noeanum, and AuNPs with minimum dilution and no turbidity was considered MIC. To determine MBC, 60 μL of MIC and three preceding chambers were cultured on Muller Hinton Agar. The minimum concentration with no bacterial growth was considered MBC. Au NPs revealed excellent antioxidant potential against DPPH, non‐toxicity property against human umbilical vein endothelial cells, and antibacterial activities against Streptococcus pneumonia, Bacillus subtilis, Staphylococcus aureus, Staphylococcus saprophyticus, Salmonella typhimurium, Pseudomonas aeruginosa, Shigella flexneri, and Escherichia coli O157:H7. These findings show that the inclusion of A. noeanum extract improves the solubility of Au NPs, which led to a notable enhancement in the antioxidant and antibacterial effects. 相似文献
24.
One of the commonly used methods to synthesize furans is the three-component reaction among aromatic aldehyde, arylamine, and acetylenedicarboxylate. The main advantages of this work are easy reaction work-up, short reaction time, high yield and easy recyclability, reusability of the catalyst. And also basalt fiber applications are surely innovative in many industrial and economic fields, because of its good mechanical, chemical and thermal performances. 相似文献
25.
2,3-Disubstituted Fluorene Scaffold for Efficient Green Phosphorescent Organic Light-Emitting Diodes
Jia-Jia Wei Yong-Jian Yang Dr. Xiang-Yang Liu Dr. Runlai Li Prof. Dr. Shu-an Li 《Chemistry (Weinheim an der Bergstrasse, Germany)》2022,28(39):e202200756
Fluorene is a classic three-membered polycyclic aromatic hydrocarbon, and it has been widely used in optoelectronic devices. Here we explore a simple and efficient strategy for the derivatization at the 2- and 3- positions in fluorene unit. By introducing different types of substituents, we design two pairs of 2,3-disubstituted fluorene isomers and use them as host materials for phosphorescent organic light-emitting diodes (PHOLEDs). The green PHOLEDs hosted by these fluorene derivatives realize high external quantum efficiencies (EQE) over 20 % with low efficiency roll-off. Particularly, the devices hosted by 2TRz3TPA and 2TPA3TRz achieve nearly 24 % EQE and 104 lm W−1 power efficiency. These results clearly demonstrate that the 2,3-disubstituted fluorene platforms are potentially useful for constructing host materials. 相似文献
26.
Martin Sweeney Darren Conboy Styliana I. Mirallai Fawaz Aldabbagh 《Molecules (Basel, Switzerland)》2021,26(9)
This review article provides a perspective on the synthesis of alicyclic and heterocyclic ring-fused benzimidazoles, imidazo[4,5-f]benzimidazoles, and imidazo[5,4-f]benzimidazoles. These heterocycles have a plethora of biological activities with the iminoquinone and quinone derivatives displaying potent bioreductive antitumor activity. Synthesis is categorized according to the cyclization reaction and mechanisms are detailed. Nitrobenzene reduction, cyclization of aryl amidines, lactams and isothiocyanates are described. Protocols include condensation, cross-dehydrogenative coupling with transition metal catalysis, annulation onto benzimidazole, often using CuI-catalysis, and radical cyclization with homolytic aromatic substitution. Many oxidative transformations are under metal-free conditions, including using thermal, photochemical, and electrochemical methods. Syntheses of diazole analogues of mitomycin C derivatives are described. Traditional oxidations of o-(cycloamino)anilines using peroxides in acid via the t-amino effect remain popular. 相似文献
27.
28.
Photoluminescence of green nanophosphors Sr2MgSi2O7 doped with Tb3+ under 374-nm excitation 下载免费PDF全文
A series of Sr2MgSi2O7:Tb3+ nanophosphors is prepared using a high-temperature solid-state reaction. The x-ray diffraction patterns show that the crystal structure of the sample is not significantly affected by Tb3+ ions. However, the images of the scanning electron microscope illustrate that the average size of nanoparticles becomes larger with the increase of Tb3+ concentration. Unlike earlier investigations on down-conversion emission of Tb3+ ion excited by deep ultraviolet light, in this work, the photoluminescence characteristics of Sr2MgSi2O7 nanophosphors doped with different Tb3+ concentrations are analyzed under 374-nm excitations. The intense green emission at 545 nm is observed at an optimal doping concentration of 1.6 mol%. The main reason for the concentration quenching is due to the electric dipole-electric dipole interaction among Tb3+ ions. 相似文献
29.
One‐Pot Synthesis of O‐Allylhydroxylamines through the Organocatalytic Oxidation of Tertiary Allylic Amines Followed by a [2,3]‐Meisenheimer Rearrangement 下载免费PDF全文
Alexis Theodorou Dr. Dimitris Limnios Prof. Dr. Christoforos G. Kokotos 《Chemistry (Weinheim an der Bergstrasse, Germany)》2015,21(13):5238-5241
A cheap, green, and highly efficient one‐pot method for the synthesis of O‐protected allylic alcohols is described. By utilizing 2,2,2‐trifluoroacetophenone as the organocatalyst and H2O2 as the oxidant, a variety of allylic amine N‐oxides were synthesized, which upon heating are converted to the final products through a [2,3]‐Meisenheimer rearrangement. 相似文献
30.
TBAI‐Catalyzed/Water‐Assisted Double C−S Bond Formations: An Efficient Approach to Sulfides through Metal‐Free Three‐Component Reactions 下载免费PDF全文
Xue‐Qiang Chu Prof. Dr. Xiao‐Ping Xu Prof. Dr. Shun‐Jun Ji 《Chemistry (Weinheim an der Bergstrasse, Germany)》2016,22(40):14181-14185
An aqueous catalytic method for double C?S bond formations that involves alcohol derivatives, organic halides, and sodium thiosulfate has been developed. A diverse range of functionalized sulfides, including pharmaceutical and biological derivatives, can be obtained in an efficient and eco‐friendly manner under air. The mechanistic studies revealed that this tetrabutylammonium‐iodide‐catalyzed/water‐assisted reaction generated a mercaptan species as the key intermediate. 相似文献